Understanding Nausea in Cancer

Nausea is common in people with cancer. It can be caused by the cancer itself, treatment, or other factors. 

Severe or prolonged nausea can take a toll on your appetite, energy, and well-being. Medications, diet, and lifestyle strategies can help manage nausea and improve your quality of life.

AI generated image of nurse comforting female patient.

What Is Nausea?

Nausea is the sensation of feeling as if you might vomit.  It can lead to vomiting, but not always. 

Symptoms and Duration of Nausea

Nausea affects each person differently. You might experience:

  • Loss of appetite that can last for a day or 2 to several weeks or months.
  • Morning nausea that improves through the day.
  • Nausea after eating, but settles between meals.
  • Nausea just before mealtimes or before certain events in the day (anticipatory nausea) that then resolves after the mealtime or event.
  • Persistent or occasional nausea with or without vomiting.
  • A metallic taste that accompanies nausea.
  • Feeling clammy or sweaty.

What Causes Nausea in Patients With Cancer?

Common causes of nausea include (1): 

  • The cancer itself.
  • Cancer treatments. 
  • Inflammation.
  • Medicines used to manage cancer and its side effects (like pain or infections).
  • Digestive problems, such as a bowel blockage, scar tissue, or a slow-moving digestive system.
  • High blood levels of toxins, electrolytes or minerals like calcium.
  • Dehydration.
  • Anxiety about the diagnosis, treatments, or fear of becoming nauseous.

Which Cancers are More Likely to Cause Nausea?

Nausea is most common with:

  • Gastrointestinal cancers, including stomach, colon, pancreatic, liver and oesophageal cancer.
  • Brain cancers and cancers that have spread to the brain.
  • Gynaecological cancers like ovarian and endometrial cancer.
  • Lung cancer.
  • Advanced cancers.

Cancer Treatment-Induced Nausea (Common Causes)

Nausea can start shortly after treatments, but sometimes there is a delay. How long it lasts depends on the treatment.

Chemotherapy-Induced Nausea

About 80% of people receiving chemotherapy experience nausea (and vomiting) from their treatment (1). Although common, chemotherapy-related nausea is often predictable and anti-nausea medications taken before treatment can prevent or reduce nausea. 

Depending on your chemotherapy regimen, nausea can be (1):

  • Acute - Starts within minutes to 24 hours after treatment, but usually stops within a day.
  • Delayed (or late-stage) - Begins after 24 hours and may persist for up to a week after treatment. It’s most common with cisplatin, carboplatin, cyclophosphamide, or anthracycline chemotherapies.
  • Anticipatory - Begins before a treatment or event that has caused nausea before, because your brain links sights, sounds, and smells to past nausea and vomiting.
  • Breakthrough - Occurs within a few days of starting a medication intended to prevent it. Your doctor might increase the dose of your anti-nausea medication, add a medication, or switch medications.
  • Refractory - Occurs when anti-nausea medication doesn’t work. You may need a different medication.

Radiotherapy-Induced Nausea

Radiotherapy can cause nausea. The dose and whether you’re also getting chemotherapy affect nausea risk.  

Radiotherapy-induced nausea can start within a few hours of treatment, and may last for several weeks. Your medical team can tell you what to expect and whether medication can help.

Surgery-Related Nausea

Nausea and vomiting can occur after surgery because of anaesthesia (drugs that put you to sleep), certain pain medicines, and other factors related to the operation. Your healthcare team can give you medicines to help prevent or manage it.

Nausea From Other Treatments

These treatments might also cause nausea:

  • Immunotherapy and targeted therapies - Some can inflame gut and brain receptors.
  • Stem cell transplants - The strong chemotherapy and/or radiotherapy required before the transplant.
  • Other medications - antibiotics, steroids, and other drugs used to manage side effects or unrelated conditions.

DID YOU KNOW?

Nausea is common with cancer and its treatments, but medications, diet modifications, and home remedies can help. Ask your care team for support.

How Is Nausea In Patients With Cancer Treated?

Medicines called antiemetics can help prevent or control nausea and vomiting. The medicine your healthcare team recommends will depend on what is causing your nausea and the cancer treatment you are receiving. Sometimes, more than one type of anti-sickness medicine is used. Take these medicines exactly as your healthcare team advises, and let them know if your nausea is not improving.

Sometimes these medications cause mild side effects such as fatigue, dizziness, headaches, or constipation. Taking them with food can help. Tell your doctor if side effects are bothersome. 

What Can Help With Nausea at Home?

When used alongside medications, diet, lifestyle, and other supportive strategies can be a helpful part of your strategy while you experience cancer nausea.

  • Eat smaller, higher-calorie meals and avoid heavy, greasy foods and those with strong flavours or smells. 
  • Your medical team may recommend using oral nutritional supplements (ONS)* if you struggle to meet your nutritional needs with normal food/normal diet alone. These are specially designed to help patients meet their specific nutritional needs when normal food cannot, with, for instance, ONS providing significant energy and protein quantities in very small volumes. They can come in the form of milkshakes, juices, soups, smoothies, puddings and more. They must always be used under the guidance of a medical professional.
  • Stay hydrated by sipping clear liquids, such as juices, broth, teas, and hydration beverages throughout the day.
  • Suck on sour, ginger, or peppermint sweets or try peppermint or ginger tea. Ginger cordial/ ale/ beer can sometimes help too. 
  • Some people find certain scents, such as peppermint or lemon, helpful, although there is limited evidence that aromatherapy reduces cancer-related nausea. 

*Oral nutritional supplements are food for special medical purposes and must be used under medical supervision.

When to Seek Medical Help

Contact your healthcare team if nausea or vomiting is making it difficult to eat or drink, if you are losing weight, or if your anti-nausea medicine is not working. Seek urgent medical advice if you have severe abdominal pain, signs of severe dehydration, or blood in your vomit. 

How Carers Can Help Someone With Nausea

As a carer, you can help someone with nausea by: 

  • Tracking their symptoms to help identify and avoid triggers.
  • Assisting with meals to ensure access to nourishing food. This might include preparing meals as well as keeping the person with cancer-related-nausea away while preparing meals and cooking (so smells and the sight of food don't cause nausea).
  • Encouraging regular fluids to prevent dehydration.
  • Helping manage their medication.
  • Offering emotional support and reassurance.

Questions to Ask Your Cancer Team About Nausea

Before cancer treatment starts, ask your doctor about your risk of nausea and how to manage it if and when it happens. These questions can guide your conversation:

  • What anti-sickness drug is best for me?
  • Should I take it before symptoms start, or is it helpful during bouts of nausea?
  • What should I do if it stops working?
  • What foods/meals should I focus on? 
  • When should I call urgently?

Key Takeaways

Nausea is a common side effect of cancer and some cancer treatments, and medicines can often help prevent or manage it. If nausea makes it difficult to eat or drink enough, your healthcare team can also advise you on ways to support your nutritional needs.

Talk to your healthcare team before treatment starts, so you have a plan in place from the start. With the right support, nausea does not have to disrupt your treatment or life.

References:

  1. [1] National Cancer Institute. Nausea and Vomiting Related to Cancer Treatment PDQ® Health Professional Version. Available at: https://www.cancer.gov/about-cancer/treatment/side-effects/nausea/nausea-hp-pdq (accessed August 25, 2026)
  2. [2] Bathula PP, Maciver MB. Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth. Int J Mol Sci. 2023;25(1):74.
  3. [3] Rambod M, Pasyar N, Karimian Z, Farbood A. The effect of lemon inhalation aromatherapy on pain, nausea, as well as vomiting and neurovascular assessment in patients for lower extremity fracture surgery: a randomized trial. BMC Complement Med Ther. 2023;23(1):208.

Disclaimer

This information is provided for educational purposes only. It is general in nature and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your healthcare team regarding any questions or concerns about your health or care.

  • Cancer
  • Treatment
  • Nausea
  • Side Effects
  • Nutrition

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